This review of the Department of Homeland Security, Science and Technology (S&T) Impact Series falls into two OODA Loop editorial and curation thematics:  Opportunities for Advantage and Innovation (Design Frameworks and Methodologies). Produced and archived over the course of 2021, the DHS S&T Impact series explores opportunities for advantage through an ongoing discussion within DHS on the definition of and framework for innovation within the agency (and private sector and interagency collaboration):   The DHS S&T Impact Series is a web and video series that “delves into the core homeland security mission areas and highlights how the Science and Technology Directorate (S&T) is helping agents, officers, first responders and decision-makers with some of their toughest challenges.”