This year’s list of biotech companies reflects the evolving impact of AI, a growing interest in cutting-edge research tools for single-cell analysis and spatial proteomics, and clinical advances for novel drug candidates that promise more convenient and effective treatment for conditions impacting millions of Americans. AlzPath’s highly sensitive blood test can detect signs of Alzheimer’s disease before symptoms develop—and in time to potentially benefit from new treatments. Genomic sequencing specialist GeneDx is helping parents discover and treat hundreds of rare diseases in newborns. 10x Genomics and Syncell streamline cutting-edge analytics for life science research, while Nabla Bio is using generative AI to design completely new antibodies. Protagonist Therapeutics is partnering with Janssen on an oral peptide for treating plaque psoriasis, aiming to expand the use of these powerful drugs beyond obesity. And Recursion is harnessing the largest supercomputer in pharma to power a drug discovery platform used by Big Pharma customers, while advancing multiple AI-based candidates of its own through clinical trials.

Full report : The 10 most innovative biotech companies of 2025 are leveraging AI to find new drugs, match patients with the best treatments, and even support biodiversity research.